Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALAD | P13716 | 2/20 | 0.56 |
| ▸ | DAO | P14920 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 3/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104097 | 0.81 | PGR (0.44) | PGR | |
| SCHEMBL2552759 | 0.78 | ERN1 (0.51) | ALAD | |
| SCHEMBL29953421 | 0.78 | RAB9A (0.51) | HDAC1 | |
| SCHEMBL505511 | 0.76 | ALAD (0.70) | ALADDAOHDAC6MMP12MMP13 | |
| SCHEMBL2557135 | 0.75 | ERN1 (0.60) | ALAD | |
| SCHEMBL2560433 | 0.75 | ALAD (0.54) | ALADDAOHDAC6 | |
| SCHEMBL27261591 | 0.74 | DAO (0.59) | ALADDAOHDAC6IKBKETBK1 | |
| SCHEMBL2556885 | 0.74 | KMO (0.56) | — | |
| SCHEMBL15332306 | 0.74 | CA12 (0.47) | DAO | |
| SCHEMBL2559288 | 0.74 | KMO (0.51) | ALADPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |