SCHEMBL28915908

SCHEMBL28915908

COC(=O)C1=NC(CC(OC)OC)=C2N=c3ccccc3=C2C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30104119 0.69 TSHR (0.33) GAATRPA1
SCHEMBL11291314 0.62 SLC6A3 (0.39)
SCHEMBL19690478 0.59 TRPA1 (0.51) TRPA1
SCHEMBL15772079 0.56 LOXL2 (0.61) GAA
SCHEMBL11182132 0.55 NPSR1 (0.38) GAATRPA1
SCHEMBL4515373 0.53 ALDH1A1 (0.32)
SCHEMBL543687 0.53 KDM4E (0.55) GAA
SCHEMBL31555404 0.52 KMT2A (0.37)
SCHEMBL21379762 0.52 GAA (0.40) GAA
SCHEMBL14764261 0.52 TAAR1 (0.52) TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115353546-A Preparation and application of oligopeptide-modified bis-indolylethyl-beta-carboline-3-carboxylic acid 首都医科大学 2022-11-18 CN disclosed