Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24639703 | 0.84 | HTR2C (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30104820 | 0.83 | ADRB1 (0.35) | ADRB1ADRB2NCF1MCHR1HTR2A | |
| SCHEMBL31244671 | 0.79 | HTR2A (0.36) | ADRB1ADRB2NCF1HTR2AHTR2C | |
| SCHEMBL30727490 | 0.77 | HTR2A (0.31) | HTR2AHTR2C | |
| SCHEMBL24640273 | 0.77 | NR3C1 (0.33) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30104836 | 0.77 | PARP1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30104859 | 0.75 | PSEN1 (0.32) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL24640572 | 0.69 | ADRB2 (0.38) | ADRB1MEN1KMT2AADRB2NCF1 | |
| SCHEMBL24640538 | 0.69 | HTR2C (0.42) | ADRB1ADRB2NCF1MCHR1HTR2A | |
| SCHEMBL24639858 | 0.67 | NR3C1 (0.33) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022247839-A1 | PARP7 INHIBITOR | 山东轩竹医药科技有限公司 | 2022-12-01 | — | — | WO | disclosed |