Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUAK1 | O60285 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | NEK2 | P51955 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104877 | 0.79 | NUAK1 (0.35) | NUAK1IGF1RMETSRCAXL | |
| SCHEMBL30104878 | 0.75 | NUAK1 (0.33) | NUAK1IGF1RMETSRCAXL | |
| SCHEMBL30104860 | 0.71 | NUAK1 (0.30) | NUAK1IGF1RMETSRCAXL | |
| SCHEMBL28400595 | 0.69 | NUAK1 (0.38) | NUAK1IGF1RMETSRCAXL | |
| SCHEMBL30104826 | 0.69 | G6PD (0.32) | — | |
| SCHEMBL30104902 | 0.67 | S100A4 (0.37) | — | |
| SCHEMBL30104856 | 0.61 | ALDH1A1 (0.35) | — | |
| SCHEMBL30104851 | 0.61 | KMT2A (0.35) | — | |
| SCHEMBL30104880 | 0.61 | NUAK1 (0.35) | NUAK1IGF1RMETSRCAXL | |
| SCHEMBL30868879 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583927-B | Thioether compound, and preparation method and application thereof | 华南师范大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-115583927-A | Thioether compound and preparation method and application thereof | 华南师范大学 | 2023-01-10 | — | — | CN | disclosed |