SCHEMBL301049

SCHEMBL301049

O=C(c1ccccc1)C(C1CO1)C1CO1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CES2 O00748 3/20 0.44
CES1 P23141 3/20 0.44
LMNA P02545 3/20 0.44
MDM2 Q00987 1/20 0.41
TSHR P16473 3/20 0.41
MAPT P10636 3/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
POLB P06746 1/20 0.41
ALDH1A1 P00352 4/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
HTT P42858 2/20 0.39
HDAC3 O15379 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
IDO1 P14902 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14198963 0.79 TDP1 (0.50) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL28080502 0.74 SLC1A2 (0.47) LMNATSHRMAPTKMT2ASMN1; SMN2
SCHEMBL8648771 0.72 TDP1 (0.42) TDP1
SCHEMBL27897064 0.72 ALDH1A1 (0.38) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL29770503 0.71 NPC1 (0.46) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL6359887 0.71 TSHR (0.50) LMNATSHRMAPTSMN1; SMN2POLB
SCHEMBL14081825 0.71 TSHR (0.50) LMNATSHRMAPTSMN1; SMN2POLB
SCHEMBL27784471 0.69 SLC6A3 (0.47) L3MBTL1LMNAKMT2ASMN1; SMN2POLB
SCHEMBL27788829 0.69 CES2 (0.46) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL27810562 0.69 CES2 (0.46) TDP1L3MBTL1CES2CES1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273520-B2 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same FUJIFILM CORPORATION (JP) 2012-09-25 US disclosed
US-8163947-B2 Cyanation catalyst and method for producing optically active cyanhydrin compound using the same NATIONAL UNIVERSITY CORPORATION, HOKKAIDO UNIVERSITY (JP) 2012-04-24 US disclosed
US-20120082836-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RESIN PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE AND METHOD FOR PRODUCTION OF RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
US-7879535-B2 A fine conductive metal pattern superior in heat resistance, adhesion property to a base surface and durability on a polyimide surface; simplification; grafting an acylic monomer on polyimide to interact with electroless plating catalyst; reduction of metal salt in defined pattern; printed circuit FUJIFILM CORPORATION (JP) 2011-02-01 US disclosed
US-7718343-B2 Decomposable resin composition and pattern-forming material including the same FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20100029977-A1 CYANATION CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYANHYDRIN COMPOUND USING THE SAME NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2010-02-04 US disclosed
US-20100003618-A1 POLYMER HAVING POLYMERIZABLE GROUP, POLYMERIZABLE COMPOSITION, PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND PLANOGRAPHIC PRINTING METHOD USING THE SAME KUNITA KAZUTO 2010-01-07 US disclosed
EP-2106906-A1 Relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM Corporation (JP) 2009-10-07 EP disclosed
US-20090246653-A1 RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE, AND METHOD OF MANUFACTURING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105795-A1 Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM Corporation (JP) 2009-09-30 EP disclosed
US-7438950-B2 Metallic pattern forming method and conductive pattern material FUJIFILM CORPORATION (JP) 2008-10-21 US disclosed
US-7416835-B2 Polymerizable composition FUJIFILM CORPORATION (JP) 2008-08-26 US disclosed
US-20080194762-A1 Polyurethanes, acryl resins, and metal (cobalt, nickel, palladium, and/or ruthenium); engravable flexographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080182205-A1 Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same KUNITA KAZUTO 2008-07-31 US disclosed
US-20080161476-A1 A binder polymer mixed with polysaccharide-modified carbon nanotubes or fullerenes and a monomer; efficient engraving with a low laser energy; improved recyclability FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-7381517-B2 Curable composition and image forming material containing the same FUJIFILM CORPORATION (JP) 2008-06-03 US disclosed
US-7374863-B2 Polyurethane binder, photoinitiator, and acrylic acid; for use as image recording layer of negative lithographic printing plate precursor; drawing with laser light FUJIFILM CORPORATION (JP) 2008-05-20 US disclosed
US-20080096132-A1 mixing a polymerizable monomer in which acrylonitrile accounts for 70% by weight or more of a total of the polymerizable monomer, water and an alkali metal persulfate polymerization initiator to conduct emulsion polymerization; distilling off unpolymerized monomers; chemical resistance film, gas barrier FUJIFILM CORPORATION 2008-04-24 US disclosed
US-7351773-B2 Polymerizable composition FUJIFILM CORPORATION (JP) 2008-04-01 US disclosed
US-20080070154-A1 DECOMPOSABLE RESIN COMPOSITION AND PATTERN-FORMING MATERIAL INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2008-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029977-A1 CYANATION CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYANHYDRIN COMPOUND USING THE SAME TYR, IK, CYB5R3 TDP1 4152/4885L3MBTL1 3502/4885CES2 2047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.