Isoformonentin

Isoformonentin

SCHEMBL30105310

COc1ccc2c(=O)c(-c3ccc(O)cc3)coc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 1.00
MAOA P21397 7/20 0.85
MAOB P27338 7/20 0.85
MAPT P10636 4/20 0.85
KDM4E B2RXH2 4/20 0.85
ALDH1A1 P00352 4/20 0.85
CYP3A4 P08684 4/20 0.85
HPGD P15428 4/20 0.85
TP53 P04637 3/20 0.85
SMN1; SMN2 Q16637 3/20 0.85
HSD17B10 Q99714 3/20 0.85
HDAC6 Q9UBN7 3/20 0.85
MEN1 O00255 2/20 0.85
KMT2A Q03164 2/20 0.85
CYP2D6 P10635 2/20 0.85
CYP2C9 P11712 2/20 0.85
CYP2C19 P33261 2/20 0.85
BCL2 P10415 1/20 0.85
IL2 P60568 1/20 0.85
CYP1B1 Q16678 1/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoformonentin SCHEMBL73338 1.00 XDH (1.00) XDHMAOAMAOBMAPTKDM4E
Formononetin SCHEMBL8416577 0.93 KDM4E (0.97) XDHMAOAMAOBMAPTKDM4E
Formononetin SCHEMBL62915 0.92 KDM4E (1.00) XDHMAOAMAOBMAPTKDM4E
Formononetin SCHEMBL29361145 0.92 KDM4E (1.00) XDHMAOAMAOBMAPTKDM4E
Formononetin SCHEMBL15271536 0.92 KDM4E (1.00) XDHMAOAMAOBMAPTKDM4E
SCHEMBL571576 0.92 XDH (0.84) XDHMAOAMAOBMAPTKDM4E
Formononetin SCHEMBL6638953 0.91 KDM4E (0.97) XDHMAOAMAOBMAPTKDM4E
SCHEMBL5814089 0.88 XDH (0.78) XDHMAOAMAOBMAPTKDM4E
SCHEMBL32659701 0.87 XDH (0.77) XDHMAOAMAOBMAPTKDM4E
SCHEMBL13774686 0.86 XDH (0.76) XDHMAOAMAOBMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119195306-A Rainwater purifying and regulating system 北京建筑大学 2024-12-27 CN disclosed
CN-117897153-A Isoflavone derivatives of the regulatory mutant bestophin 1 for the treatment of BEST 1-related retinopathy 雷根斯堡大学 2024-04-16 CN disclosed
WO-2022247839-A1 PARP7 INHIBITOR 山东轩竹医药科技有限公司 2022-12-01 WO disclosed