Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 9/20 | 0.76 |
| ▸ | RAB9A | P51151 | 8/20 | 0.76 |
| ▸ | NPC1 | O15118 | 6/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | MAOA | P21397 | 3/20 | 0.68 |
| ▸ | MAOB | P27338 | 3/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.68 |
| ▸ | BCL2 | P10415 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | IL2 | P60568 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571576 | 0.92 | XDH (0.84) | XDHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8481488 | 0.89 | PIN1 (0.73) | XDHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5814089 | 0.88 | XDH (0.78) | XDHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22340136 | 0.86 | XDH (0.76) | XDHMAPTRAB9ANPC1SMN1; SMN2 | |
| Isoformonentin SCHEMBL30105310 | 0.86 | XDH (1.00) | XDHMAPTRAB9ANPC1SMN1; SMN2 | |
| Isoformonentin SCHEMBL73338 | 0.86 | XDH (1.00) | XDHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12289033 | 0.86 | XDH (0.76) | XDHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL762092 | 0.86 | MAPT (1.00) | XDHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL470779 | 0.85 | STS (0.60) | XDHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4434901 | 0.85 | RAB9A (0.78) | XDHMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192152-A1 | Novel Antigiardial Agents and Methods of Use Thereof | UNIVERSITY OF MISSISSIPPI | 2009-07-30 | — | — | US | disclosed |
| US-7468445-B2 | Antigiardial agents and use thereof | UNIVERSITY OF MISSISSIPPI (US) | 2008-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192152-A1 | Novel Antigiardial Agents and Methods of Use Thereof | ENPP2, GPER1, ALPI | XDH 2105/4885MAPT 4737/4885RAB9A 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.