SCHEMBL301059

SCHEMBL301059

CC(C)P(c1ccccc1)C(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.45
CYP3A4 P08684 1/20 0.45
TAAR1 Q96RJ0 4/20 0.39
SIGMAR1 Q99720 4/20 0.39
SLC6A2 P23975 2/20 0.39
MAOA P21397 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
CYP2A6 P11509 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
ESR1 P03372 4/20 0.37
ESR2 Q92731 4/20 0.37
SLC18A2 Q05940 1/20 0.36
CYP2D6 P10635 1/20 0.36
TP53 P04637 1/20 0.35
TRPA1 O75762 1/20 0.34
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1241416 0.97 TDP1 (0.43) TDP1CYP3A4TAAR1SIGMAR1SLC6A2
SCHEMBL1742459 0.90 TDP1 (0.38) TDP1CYP3A4TAAR1SIGMAR1SLC6A2
SCHEMBL9075669 0.84
SCHEMBL4587077 0.81 SLC6A2 (0.32) TDP1CYP3A4TAAR1SIGMAR1SLC6A2
SCHEMBL11853866 0.81 SIGMAR1 (0.34) TDP1CYP3A4TAAR1SIGMAR1SLC6A2
SCHEMBL5596879 0.78 CYP3A4 (0.41) TDP1CYP3A4ESR1ESR2CYP2D6
SCHEMBL301134 0.77 TDP1 (0.45) TDP1CYP3A4TAAR1SIGMAR1SLC6A2
SCHEMBL4398254 0.76 TDP1 (0.39) TDP1CYP3A4TAAR1SIGMAR1SLC6A2
SCHEMBL6288575 0.76 TAAR1 (0.40) TDP1CYP3A4TAAR1CYP2D6LMNA
SCHEMBL28579756 0.76 CYP3A4 (0.46) TDP1CYP3A4TAAR1SIGMAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-112745210-B Method for preparing alpha, beta-unsaturated carboxylic acid compound 中国科学院大连化学物理研究所 2022-02-15 CN claimed
CN-112745210-A Method for preparing alpha, beta-unsaturated carboxylic acid compound 中国科学院大连化学物理研究所 2021-05-04 CN claimed
CN-110724047-B Method for preparing aromatic carboxylic acid compound 中国科学院大连化学物理研究所 2020-10-30 CN claimed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN claimed
CN-110724047-A Method for preparing aromatic carboxylic acid compound 中国科学院大连化学物理研究所 2020-01-24 CN claimed
CN-102731495-B Synthetic method of tetrahydroisoquinoline compound UNIV CHINA AGRICULTURAL 2015-04-08 CN claimed
CN-103483217-B Method for synthesizing doxycycline hydrochloride intermediate alpha-6-doxycycline through hydrogenation on basis of silica gel rhodium catalyst UNIV HENAN NORMAL 2015-03-04 CN claimed
CN-103467335-B Method for synthesizing doxycycline hydrochloride intermediate alpha-6-deoxytetracycline based on hydrogenation of carbon-based rhodium catalyst HENAN NORMAL UNIVERSITY (CN) 2014-10-15 CN claimed
CN-102408428-B 1,2-oxinane pyrazolidone compounds and preparation method and applications thereof UNIV CHINA AGRICULTURAL 2014-01-15 CN claimed
US-7615658-B2 Aldehyde and alcohol compositions derived from seed oils DOW GLOBAL TECHNOLOGIES, INC. (US) 2009-11-10 US claimed
CN-100497288-C Aldehyde and alcohol compositions from seed oils DOW GLOBAL TECHNOLOGIES INC (US) 2009-06-10 CN claimed
CN-101326191-A Phosphine transition metal complex, method for producing same and antitumor agent containing same NIPPON CHEMICAL IND (JP) 2008-12-17 CN claimed
US-20060193802-A1 Aldehyde and alcohol compositions derived from seed oils DOW GLOBAL TECHNOLOGIES LLC 2006-08-31 US claimed
CN-1780808-A Aldehyde and alcohol compositions derived from seed oils DOW GLOBAL TECHNOLOGIES INC (US) 2006-05-31 CN claimed
EP-1620387-A2 ALDEHYDE AND ALCOHOL COMPOSITIONS DERIVED FROM SEED OILS DOW GLOBAL TECHNOLOGIES INC. (US) 2006-02-01 EP claimed
WO-2004096744-A2 ALDEHYDE AND ALCOHOL COMPOSITIONS DERIVED FROM SEED OILS DOW GLOBAL TECHNOLGIES INC. (US) 2004-11-11 WO claimed
EP-0028378-B1 IMPROVED HYDROFORMYLATION PROCESS USING STABLE RHODIUM CATALYST UNION CARBIDE CORPORATION (US) 1985-01-09 EP claimed
US-4283562-A COMPLEXED WITH CARBON MONOXIDE AND A PHENYL PHOSPHINE UNION CARBIDE CORPORATION (US) 1981-08-11 US claimed
EP-0028378-A1 Improved hydroformylation process using stable rhodium catalyst UNION CARBIDE CORPORATION (US) 1981-05-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060193802-A1 Aldehyde and alcohol compositions derived from seed oils HACL2, FASN, PFAS TDP1 2580/4885CYP3A4 1175/4885TAAR1 1030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.