Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066892 | 0.79 | CYP3A4 (0.41) | CYP3A4TDP1ESR1ESR2LMNA | |
| SCHEMBL301059 | 0.78 | TDP1 (0.45) | CYP3A4TDP1ESR1ESR2LMNA | |
| SCHEMBL1241416 | 0.76 | TDP1 (0.43) | CYP3A4TDP1ESR1ESR2CYP2D6 | |
| SCHEMBL5596161 | 0.73 | TSHR (0.41) | TDP1ESR2ALDH1A1ALOX15TSHR | |
| SCHEMBL28508279 | 0.73 | PTGS2 (0.41) | CYP3A4TDP1ESR1ESR2LMNA | |
| SCHEMBL6288575 | 0.72 | TAAR1 (0.40) | CYP3A4TDP1LMNAADRA2CKDM4E | |
| SCHEMBL9330599 | 0.72 | LMNA (0.41) | CYP3A4TDP1LMNAADRA2CKDM4E | |
| SCHEMBL4398254 | 0.72 | TDP1 (0.39) | CYP3A4TDP1ESR1ESR2TRPA1 | |
| SCHEMBL28696732 | 0.70 | LMNA (0.35) | CYP3A4TDP1ESR1ESR2LMNA | |
| SCHEMBL6569417 | 0.70 | LMNA (0.38) | CYP3A4TDP1ESR1ESR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |
| US-4855507-A | FOR FROTH FLOTATION AND FIREPROOFING | AMERICAN CYANAMID COMPANY (US) | 1989-08-08 | — | — | US | disclosed |