⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30106008 | 0.89 | DGAT1 (0.32) | — | |
| SCHEMBL23908133 | 0.82 | — | — | |
| SCHEMBL20767594 | 0.80 | ALDH1A1 (0.37) | — | |
| SCHEMBL20767654 | 0.78 | GBA1 (0.35) | — | |
| SCHEMBL20767653 | 0.78 | GBA1 (0.35) | — | |
| SCHEMBL30106041 | 0.74 | — | — | |
| SCHEMBL21751511 | 0.74 | MTNR1A (0.37) | — | |
| SCHEMBL21751510 | 0.74 | MTNR1A (0.37) | — | |
| SCHEMBL29748502 | 0.73 | — | — | |
| SCHEMBL30154394 | 0.73 | PCSK9 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110298-A1 | HOT MELT EXTRUDED SOLID DISPERSIONS CONTAINING A BCL2 INHIBITOR | Guangzhou Lupeng Pharmaceutical Company Ltd. (CN) | 2023-01-04 | — | — | EP | disclosed |