Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189069 | 0.92 | CASP6 (0.50) | CASP6TRPV1IKBKBDGAT1GSK3B | |
| SCHEMBL30106349 | 0.92 | CASP6 (0.50) | CASP6TRPV1IKBKBDGAT1GSK3B | |
| SCHEMBL27189103 | 0.90 | IKBKB (0.46) | CASP6TRPV1IKBKBDGAT1GSK3B | |
| SCHEMBL27189073 | 0.89 | DGAT1 (0.49) | CASP6TRPV1IKBKBDGAT1GSK3B | |
| SCHEMBL27189106 | 0.88 | SMN1; SMN2 (0.54) | CASP6TRPV1IKBKBGSK3BNPC1 | |
| SCHEMBL29158605 | 0.88 | CASP6 (0.43) | CASP6TRPV1IKBKBDGAT1HDAC6 | |
| SCHEMBL27189116 | 0.88 | IKBKB (0.48) | TRPV1IKBKBDGAT1GSK3BHDAC6 | |
| SCHEMBL29158717 | 0.87 | IKBKB (0.46) | CASP6TRPV1IKBKBDGAT1GSK3B | |
| SCHEMBL30740883 | 0.87 | IKBKB (0.46) | CASP6TRPV1IKBKBDGAT1GSK3B | |
| SCHEMBL30740892 | 0.87 | CASP6 (0.44) | CASP6TRPV1IKBKBDGAT1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255764-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | claimed |
| WO-2022255764-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | disclosed |