Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 6/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189066 | 1.00 | CASP6 (0.44) | CASP6EGLN1ABL1ADORA2APTPN5 | |
| SCHEMBL30106290 | 0.87 | CASP6 (0.45) | CASP6IKBKBHSP90AA1HSP90AB1TRPV1 | |
| SCHEMBL29158613 | 0.85 | TARBP2 (0.48) | PTPN5IKBKBHSP90AA1PTGDR2 | |
| SCHEMBL27189073 | 0.85 | DGAT1 (0.49) | CASP6EGLN1IKBKBTRPV1DGAT1 | |
| SCHEMBL29158605 | 0.84 | CASP6 (0.43) | CASP6IKBKBHSP90AA1HSP90AB1TRPV1 | |
| SCHEMBL27189106 | 0.84 | SMN1; SMN2 (0.54) | CASP6IKBKBHSP90AA1HSP90AB1TRPV1 | |
| SCHEMBL29158717 | 0.83 | IKBKB (0.46) | CASP6IKBKBHSP90AA1HSP90AB1TRPV1 | |
| SCHEMBL30740883 | 0.83 | IKBKB (0.46) | CASP6IKBKBHSP90AA1HSP90AB1TRPV1 | |
| SCHEMBL27189103 | 0.82 | IKBKB (0.46) | CASP6IKBKBHSP90AA1HSP90AB1TRPV1 | |
| SCHEMBL30106359 | 0.82 | GSK3B (0.51) | IKBKBHSP90AA1HSP90AB1TRPV1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |