Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.46 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | ESRRB | O95718 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189062 | 0.85 | DGAT1 (0.48) | DGAT1FAAHTP53SMN1; SMN2PPARD | |
| SCHEMBL29158684 | 0.85 | POLB (0.44) | TAAR1DGAT1HDAC4SLC6A5PLAAT3 | |
| SCHEMBL27189073 | 0.83 | DGAT1 (0.49) | DGAT1HDAC4 | |
| SCHEMBL30106389 | 0.83 | HDAC4 (0.48) | DGAT1HDAC4KDM4E | |
| SCHEMBL27189116 | 0.82 | IKBKB (0.48) | DGAT1HDAC4PPARGPPARD | |
| SCHEMBL29158719 | 0.79 | CD274 (0.49) | HDAC4EPHX2 | |
| SCHEMBL29158755 | 0.79 | RAB9A (0.43) | TAAR1HDAC4PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL30106348 | 0.78 | GSK3B (0.49) | DGAT1SMN1; SMN2 | |
| SCHEMBL30106349 | 0.78 | CASP6 (0.50) | DGAT1TP53MAPTLMNA | |
| SCHEMBL27189069 | 0.78 | CASP6 (0.50) | DGAT1TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255764-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | disclosed |