Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2079041 | 0.84 | TSHR (0.39) | CYP2A6CYP1A2HSD17B10TSHRHIF1A | |
| SCHEMBL29583333 | 0.84 | TSHR (0.39) | CYP2A6CYP1A2HSD17B10TSHRHIF1A | |
| SCHEMBL27948130 | 0.82 | CYP1A2 (0.42) | CYP2A6CYP1A2HSD17B10TSHRHIF1A | |
| Hydrochloric Acid SCHEMBL7943424 | 0.81 | RAB9A (0.40) | CYP2A6CYP1A2HSD17B10TSHRHIF1A | |
| Hydrochloric Acid SCHEMBL7943427 | 0.81 | TSHR (0.37) | CYP2A6CYP1A2HSD17B10TSHRHIF1A | |
| SCHEMBL2824075 | 0.80 | HSD17B10 (0.44) | CYP2A6CYP1A2HSD17B10TSHRHIF1A | |
| SCHEMBL29489770 | 0.80 | HSD17B10 (0.44) | CYP2A6CYP1A2HSD17B10TSHRHIF1A | |
| SCHEMBL29489771 | 0.80 | HSD17B10 (0.44) | CYP2A6CYP1A2HSD17B10TSHRHIF1A | |
| SCHEMBL7943430 | 0.79 | TSHR (0.35) | CYP2A6CYP1A2HSD17B10TSHRHIF1A | |
| SCHEMBL1925968 | 0.79 | MAPT (0.40) | CYP2A6CYP1A2HSD17B10TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481618-B2 | Cyclopolyarylene compound and method of manufacturing same | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2016-11-01 | — | — | US | disclosed |
| EP-2610248-B1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE BY MEANS OF COUPLING METHOD USING A PALLADIUM COMPOUND | TEIJIN PHARMA LTD (JP) | 2016-06-08 | — | — | EP | disclosed |
| US-9266909-B2 | Cyclic compound containing functional group or containing no functional group, and method for producing same | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2016-02-23 | — | — | US | disclosed |
| US-9242937-B2 | Pharmaceutically active disubstituted pyridine derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-26 | — | — | US | disclosed |
| EP-2681193-B1 | PHARMACEUTICALLY ACTIVE DISUBSTITUTED PYRIDINE DERIVATIVES | LEAD DISCOVERY CENTER GMBH (DE) | 2016-01-06 | — | — | EP | disclosed |
| US-20150126779-A1 | CYCLIC COMPOUND CONTAINING FUNCTIONAL GROUP OR CONTAINING NO FUNCTIONAL GROUP, AND METHOD FOR PRODUCING SAME | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-05-07 | — | — | US | disclosed |
| US-8952174-B2 | Process for producing phenyl-substituted heterocyclic derivative through coupling using transition metal catalyst | TEIJIN PHARMA LIMITED (JP) | 2015-02-10 | — | — | US | disclosed |
| US-8916714-B2 | Method for producing phenyl-substituted heterocyclic derivative by means of coupling method using palladium compound | TEIJIN PHARMA LIMITED (JP) | 2014-12-23 | — | — | US | disclosed |
| US-20140296304-A1 | Pharmaceutically Active Disubstituted Pyridine Derivatives | LEAD DISCOVERY CENTER GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| US-20140066661-A1 | CYCLOPOLYARYLENE COMPOUND AND METHOD OF MANUFACTURING SAME | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-03-06 | — | — | US | disclosed |
| EP-1741693-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE ALCOHOLS | Nagoya Industrial Science Research Institute (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-20060167300-A1 | Process for producing optically active ss-hydroxy alpha aminocarboxylic acid derivative | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1650185-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE BETA-HYDROXY- ALPHA-AMINOCARBOXYLIC ACID DERIVATIVES | Nissan Chemical Industries, Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
| EP-0768288-B1 | Process for preparing optically active cyclohexanol derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-5756863-A | Process for preparing optically active cyclohexanol derivatives | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-05-26 | — | — | US | disclosed |
| US-5686616-A | Process for preparing an optically active amine | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0768288-A2 | Process for preparing optically active cyclohexanol derivatives | Takasago International Corporation (JP) | 1997-04-16 | — | — | EP | disclosed |
| EP-0479541-B1 | Iridium-optically active phosphine complex and catalytic production of optically active alcohols therewith | TAKASAGO PERFUMERY CO LTD (JP) | 1995-07-19 | — | — | EP | disclosed |
| US-5210332-A | Iridium-optically active phosphine complex and process for producing optically active alcohols using the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0479541-A1 | Iridium-optically active phosphine complex and catalytic production of optically active alcohols therewith | Takasago International Corporation (JP) | 1992-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296304-A1 | Pharmaceutically Active Disubstituted Pyridine Derivatives | PINK1, PDPK1, LCK | CYP2A6 3346/4885CYP1A2 2457/4885HSD17B10 3882/4885 |
| US-20140066661-A1 | CYCLOPOLYARYLENE COMPOUND AND METHOD OF MANUFACTURING SAME | CYP1B1, CYP51A1, CYP1A1 | CYP2A6 60/4885CYP1A2 4/4885HSD17B10 41/4885 |
| US-20060167300-A1 | Process for producing optically active ss-hydroxy alpha aminocarboxylic acid derivative | ALDH7A1, HCAR1, ALAD | CYP2A6 291/4885CYP1A2 237/4885HSD17B10 32/4885 |
| US-20150126779-A1 | CYCLIC COMPOUND CONTAINING FUNCTIONAL GROUP OR CONTAINING NO FUNCTIONAL GROUP, AND METHOD FOR PRODUCING SAME | CYP1B1, BCR, DDT | CYP2A6 103/4885CYP1A2 20/4885HSD17B10 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.