Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | SDHB | P21912 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 4/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | BCR | P11274 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718372 | 0.85 | CNR1 (0.56) | CDK8GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4895475 | 0.84 | GABRG2 (0.66) | CDK8GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4901644 | 0.84 | TP53 (0.50) | NPC1RAB9A | |
| SCHEMBL13680584 | 0.83 | GABRG2 (0.53) | CDK8GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6714723 | 0.82 | CA12 (0.52) | CDK8GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28680245 | 0.81 | CDK8 (0.54) | CDK8GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16553302 | 0.80 | GABRG2 (0.53) | CDK8GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL67941 | 0.80 | CA12 (0.68) | CDK8GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL21790698 | 0.79 | GABRG2 (0.50) | CDK8GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6717982 | 0.79 | CNR1 (0.55) | CDK8GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |