Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108044 | 0.85 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL30108032 | 0.83 | KDM4E (0.47) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL30108073 | 0.82 | LPL (0.40) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL30107959 | 0.71 | KDM4E (0.44) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL30107951 | 0.71 | PTGS1 (0.46) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL30107973 | 0.71 | KDM4E (0.46) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL30108012 | 0.70 | TSHR (0.58) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL30108014 | 0.69 | KDM4E (0.42) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL30108013 | 0.68 | HPGD (0.53) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL30108023 | 0.68 | PTGS1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |