Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108043 | 0.87 | ADORA2A (0.41) | KDM4EALDH1A1MAPTRAB9AMCL1 | |
| SCHEMBL30108062 | 0.86 | MAPT (0.39) | KDM4EALDH1A1MAPTRAB9AMCL1 | |
| SCHEMBL30108066 | 0.73 | ADORA2A (0.44) | KDM4EALDH1A1MAPTRAB9AMCL1 | |
| SCHEMBL30107952 | 0.73 | ADORA2A (0.41) | KDM4EALDH1A1RAB9AHTTMAPK10 | |
| SCHEMBL30108049 | 0.72 | TSHR (0.45) | KDM4EALDH1A1RAB9AHPGDHTT | |
| SCHEMBL30108034 | 0.71 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTRAB9AMCL1 | |
| SCHEMBL30108022 | 0.71 | SLC6A2 (0.37) | MAPK10ADORA2AADORA1 | |
| SCHEMBL21642883 | 0.71 | MAPK10 (0.63) | MAPK10 | |
| SCHEMBL21642831 | 0.70 | MAPK10 (0.49) | MAPK10PIK3CDPIK3CA | |
| SCHEMBL21642869 | 0.68 | MAPK10 (0.54) | TDP1MAPK10PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |