Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.45 |
| ▸ | GABRP | O00591 | 6/20 | 0.45 |
| ▸ | GABRD | O14764 | 6/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.45 |
| ▸ | GABRE | P78334 | 6/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19555950 | 1.00 | CYP1A2 (0.47) | CYP1A2NPC1SMN1; SMN2RAB9AGABRA1 | |
| SCHEMBL28551286 | 0.83 | RAB9A (0.57) | CYP1A2NPC1SMN1; SMN2RAB9AGABRA1 | |
| SCHEMBL28911125 | 0.83 | KMT2A (0.48) | CYP1A2NPC1SMN1; SMN2RAB9AGABRA1 | |
| SCHEMBL11399731 | 0.83 | NPC1 (0.49) | CYP1A2NPC1SMN1; SMN2RAB9AGABRA1 | |
| SCHEMBL29031128 | 0.82 | SMN1; SMN2 (0.47) | CYP1A2NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL28543158 | 0.81 | SMN1; SMN2 (0.53) | CYP1A2NPC1SMN1; SMN2RAB9AGABRA1 | |
| SCHEMBL28532069 | 0.81 | ALDH1A1 (0.54) | CYP1A2NPC1SMN1; SMN2RAB9AGABRA2 | |
| SCHEMBL18405340 | 0.80 | P4HTM (0.60) | CYP1A2ADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL30112058 | 0.80 | P4HTM (0.60) | CYP1A2ADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL347328 | 0.79 | CYP1A2 (0.51) | CYP1A2NPC1SMN1; SMN2RAB9AGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204009-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-109641854-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2023-02-03 | — | — | CN | disclosed |