Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | RAD52 | P43351 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19555950 | 0.83 | CYP1A2 (0.47) | KMT2AKDM4EMEN1CYP1A2LMNA | |
| SCHEMBL30112066 | 0.83 | CYP1A2 (0.47) | KMT2AKDM4EMEN1CYP1A2LMNA | |
| SCHEMBL21835783 | 0.83 | HDAC2 (0.50) | KMT2AKDM4EMEN1GAAPOLB | |
| SCHEMBL5067501 | 0.79 | LMNA (0.67) | KMT2AKDM4EMEN1GAAPOLB | |
| SCHEMBL28532069 | 0.77 | ALDH1A1 (0.54) | KMT2AKDM4EMEN1GAAPOLB | |
| SCHEMBL28551286 | 0.76 | RAB9A (0.57) | KMT2AKDM4EMEN1GAACYP1A2 | |
| SCHEMBL11399731 | 0.76 | NPC1 (0.49) | KMT2AKDM4EMEN1POLBCYP1A2 | |
| SCHEMBL347328 | 0.75 | CYP1A2 (0.51) | KMT2AKDM4EMEN1POLBCYP1A2 | |
| SCHEMBL29031128 | 0.75 | SMN1; SMN2 (0.47) | KMT2AKDM4EMEN1GAACYP1A2 | |
| SCHEMBL21835789 | 0.75 | MAOB (0.52) | KMT2AKDM4EMEN1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925357-B | Acylhydrazone compound, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2023-06-06 | — | — | CN | disclosed |
| CN-111925357-A | Acylhydrazone compound, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2020-11-13 | — | — | CN | disclosed |