Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 14/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 14/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30032715 | 0.84 | MAP4K1 (0.41) | GRIN1GRIN2BDGAT1NR3C1 | |
| SCHEMBL28905437 | 0.84 | MAP4K1 (0.41) | GRIN1GRIN2BDGAT1NR3C1 | |
| SCHEMBL28905433 | 0.83 | SCN9A (0.33) | GRIN1GRIN2BHTR2AHTR2CDGAT1 | |
| SCHEMBL19950357 | 0.77 | MAP4K1 (0.51) | — | |
| SCHEMBL20353705 | 0.76 | DGAT1 (0.36) | GRIN1GRIN2BDGAT1 | |
| SCHEMBL29913785 | 0.76 | DGAT1 (0.36) | GRIN1GRIN2BDGAT1 | |
| SCHEMBL30112276 | 0.75 | DGAT1 (0.39) | HTR2AHTR2CDGAT1NR3C1 | |
| SCHEMBL759979 | 0.73 | CYP11B2 (0.43) | HDAC8DGAT1 | |
| SCHEMBL23165476 | 0.71 | LMNA (0.39) | HDAC8DGAT1 | |
| SCHEMBL5518025 | 0.71 | TRPA1 (0.60) | GRIN1GRIN2BDGAT1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253328-A1 | COMPOUND HAVING KINASE INHIBITORY FUNCTION, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 轶诺(浙江)药业有限公司 | 2022-12-08 | — | — | WO | disclosed |