Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.41 |
| ▸ | MAP3K11 | Q16584 | 5/20 | 0.41 |
| ▸ | SGK1 | O00141 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154787 | 0.72 | MAP3K11 (0.51) | MAP3K11SGK1CDK8AXLCLK1 | |
| SCHEMBL27851403 | 0.70 | MAPT (0.36) | CYP3A4 | |
| SCHEMBL27850881 | 0.70 | ESR1 (0.39) | CYP3A4 | |
| SCHEMBL27603372 | 0.69 | CYP3A4 (0.35) | CYP3A4 | |
| SCHEMBL4154994 | 0.69 | AXL (0.45) | MAP3K11SGK1CDK8AXLCLK1 | |
| SCHEMBL27697912 | 0.69 | GABRG2 (0.32) | CYP3A4 | |
| SCHEMBL28791680 | 0.68 | CYP3A4 (0.36) | CYP3A4 | |
| SCHEMBL27588055 | 0.67 | CYP4F2 (0.36) | CYP3A4 | |
| SCHEMBL5549486 | 0.66 | CDK8 (0.42) | AAK1SGK1CDK8AXLCYP3A4 | |
| SCHEMBL4159593 | 0.65 | AXL (0.69) | MAP3K11SGK1CDK8AXLKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548867-B2 | Amido compounds as AhR modulators | IDEA YA BIOSCIENCES, INC. (US) | 2023-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548867-B2 | Amido compounds as AhR modulators | AHR, ARNT, RXRB | AAK1 2874/4885MAP3K11 2746/4885SGK1 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.