Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 7/20 | 0.53 |
| ▸ | MAP2 | P11137 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 7/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28517848 | 1.00 | RHEB (0.53) | RHEBMAP2SCN9APOLBNPSR1 | |
| SCHEMBL25719933 | 0.86 | RORC (0.43) | RHEBPOLBNPSR1RORC | |
| SCHEMBL28508959 | 0.85 | RHEB (0.44) | RHEBMAP2RORC | |
| SCHEMBL30116523 | 0.83 | TRPA1 (0.44) | RHEBTRPA1 | |
| SCHEMBL28508944 | 0.83 | TRPA1 (0.44) | RHEBTRPA1 | |
| SCHEMBL28511997 | 0.82 | RHEB (0.48) | RHEB | |
| SCHEMBL30116444 | 0.82 | RHEB (0.48) | RHEB | |
| SCHEMBL25719185 | 0.82 | RORC (0.40) | RHEBRORC | |
| SCHEMBL28517406 | 0.82 | RHEB (0.46) | RHEB | |
| SCHEMBL30116420 | 0.82 | RHEB (0.46) | RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112135611-B | Benzimidazole derivatives as modulators of retinoic acid-related orphan receptor gamma (ROR γ) and pharmaceutical uses thereof | 江苏恒瑞医药股份有限公司 | 2023-01-31 | — | — | CN | disclosed |