Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 9/20 | 0.43 |
| ▸ | PTGES | O14684 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28508944 | 1.00 | TRPA1 (0.44) | TRPA1TRPM8TRPV1RHEBPTGES | |
| SCHEMBL28511997 | 0.85 | RHEB (0.48) | RHEBTDP1 | |
| SCHEMBL30116444 | 0.85 | RHEB (0.48) | RHEBTDP1 | |
| SCHEMBL28517406 | 0.84 | RHEB (0.46) | RHEBTDP1 | |
| SCHEMBL30116420 | 0.84 | RHEB (0.46) | RHEBTDP1 | |
| SCHEMBL28517848 | 0.83 | RHEB (0.53) | TRPA1RHEB | |
| SCHEMBL30116414 | 0.83 | RHEB (0.53) | TRPA1RHEB | |
| SCHEMBL25719261 | 0.80 | CACNA1H (0.41) | TRPA1TRPM8TRPV1RHEBPTGES | |
| SCHEMBL23000359 | 0.79 | RORC (0.40) | TRPA1TRPM8TRPV1PTGESCACNA1H | |
| SCHEMBL23000519 | 0.79 | CACNA1H (0.39) | TRPA1TRPM8TRPV1PTGESCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112135611-B | Benzimidazole derivatives as modulators of retinoic acid-related orphan receptor gamma (ROR γ) and pharmaceutical uses thereof | 江苏恒瑞医药股份有限公司 | 2023-01-31 | — | — | CN | disclosed |