Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744272 | 1.00 | CYP26A1 (0.47) | CYP26A1CYP26B1PTGDR2TDP1KIF11 | |
| SCHEMBL16799139 | 0.86 | KIF11 (0.47) | CYP26A1CYP26B1PTGDR2KIF11CA2 | |
| SCHEMBL16224728 | 0.85 | CYP26A1 (0.48) | CYP26A1CYP26B1PTGDR2TDP1CYP1A2 | |
| SCHEMBL23488069 | 0.83 | KIF11 (0.42) | CYP26A1CYP26B1PTGDR2TDP1KIF11 | |
| SCHEMBL15955958 | 0.83 | CYP26A1 (0.42) | CYP26A1CYP26B1PTGDR2CA2MMP1 | |
| SCHEMBL16888037 | 0.82 | ALDH1A1 (0.51) | PTGDR2TDP1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14744197 | 0.82 | GAA (0.47) | PTGDR2PKMMEN1KMT2A | |
| SCHEMBL28512005 | 0.81 | CA2 (0.47) | PTGDR2KIF11CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16888036 | 0.81 | PTGDR2 (0.53) | PTGDR2TDP1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30026587 | 0.79 | CA2 (0.56) | PTGDR2KIF11CA2PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112135611-B | Benzimidazole derivatives as modulators of retinoic acid-related orphan receptor gamma (ROR γ) and pharmaceutical uses thereof | 江苏恒瑞医药股份有限公司 | 2023-01-31 | — | — | CN | disclosed |