Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7940896 | 0.79 | ODC1 (0.44) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL29001334 | 0.78 | ODC1 (0.43) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL6151309 | 0.77 | ODC1 (0.41) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL6151308 | 0.77 | ODC1 (0.41) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL1249526 | 0.74 | ODC1 (0.40) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL5069038 | 0.72 | CHRM2 (0.40) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL28113559 | 0.69 | ODC1 (0.54) | ODC1LMNABLMKDM4EMAPT | |
| Eflornithine, (S)- SCHEMBL60698 | 0.67 | ODC1 (1.00) | ODC1LMNABLMKDM4EMAPT | |
| D-Eflornithine SCHEMBL60699 | 0.67 | ODC1 (1.00) | ODC1LMNABLMKDM4EMAPT | |
| Eflornithine SCHEMBL8581344 | 0.67 | ODC1 (1.00) | ODC1LMNABLMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022245186-A1 | ANTIBODY-DRUG CONJUGATE THAT BINDS TO ROR1 AND B7-H3, AND USE THEREOF | 주식회사 레고켐바이오사이언스 | 2022-11-24 | — | — | WO | claimed |