Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29001334 | 0.83 | ODC1 (0.43) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL6151309 | 0.82 | ODC1 (0.41) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL6151308 | 0.82 | ODC1 (0.41) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL5069038 | 0.81 | CHRM2 (0.40) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL30116554 | 0.79 | ODC1 (0.50) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL1249526 | 0.79 | ODC1 (0.40) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL15909004 | 0.72 | CES2 (0.38) | KMT2ACYP1A2MEN1 | |
| SCHEMBL15909003 | 0.72 | CES2 (0.38) | KMT2ACYP1A2MEN1 | |
| SCHEMBL28113559 | 0.70 | ODC1 (0.54) | ODC1LMNABLMKDM4EMAPT | |
| Trifluoroacetic Acid SCHEMBL31080805 | 0.69 | ODC1 (0.48) | ODC1LMNABLMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448556-A1 | CELL PENETRATING POLYPEPTIDES (CPPS) AND THEIR USE IN HUMAN THERAPY | RDP Pharma AG (CH) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023111213-A1 | CELL PENETRATING POLYPEPTIDES (CPPS) AND THEIR USE IN HUMAN THERAPY | RDP PHARMA AG (CH) | 2023-06-22 | — | — | WO | disclosed |
| EP-1067919-A1 | DFMO AND SULINDAC COMBINATION IN CANCER CHEMOPREVENTION | THE ARIZONA BOARD OF REGENTS on behalf of THE UNIVERSITY OF ARIZONA (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999049859-A9 | DFMO AND SULINDAC COMBINATION IN CANCER CHEMOPREVENTION | UNIV ARIZONA (US) | 1999-11-25 | — | — | WO | disclosed |
| WO-1999049859-A1 | DFMO AND SULINDAC COMBINATION IN CANCER CHEMOPREVENTION | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 1999-10-07 | — | — | WO | disclosed |