Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.47 |
| ▸ | EIF4E | P06730 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557826 | 0.87 | CASP6 (0.66) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL30011381 | 0.85 | CASP6 (0.64) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL23499234 | 0.85 | CASP6 (0.64) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL5207567 | 0.84 | KDM4E (0.47) | CYP2C8CASP6TTRTSHRLMNA | |
| SCHEMBL5207404 | 0.84 | RAB9A (0.55) | TTRLMNAEIF4E | |
| SCHEMBL99918 | 0.82 | CASP6 (0.64) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL17197945 | 0.82 | CASP6 (0.68) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL12181972 | 0.81 | CASP6 (0.58) | CASP6TSHRLMNASRD5A2HCAR3 | |
| SCHEMBL11761556 | 0.81 | CASP6 (0.58) | CASP6TSHRLMNAHCAR3 | |
| SCHEMBL4597071 | 0.81 | CYP2C8 (0.65) | CYP2C8AKR1C3AKR1C2MAP4K4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409223-B | Amide compound and medical application thereof as STING inhibitor | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |