Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934926 | 0.81 | FOLH1 (0.46) | — | |
| SCHEMBL8934928 | 0.81 | FOLH1 (0.46) | — | |
| SCHEMBL34475333 | 0.80 | FOLH1 (0.44) | — | |
| SCHEMBL8934904 | 0.78 | KMT2A (0.40) | GNAI3GNAO1GNAI1OPRD1ITGB3 | |
| SCHEMBL8934927 | 0.78 | KMT2A (0.40) | GNAI3GNAO1GNAI1OPRD1ITGB3 | |
| SCHEMBL4529797 | 0.77 | POLB (0.49) | ITGB3ITGA2BSIGMAR1POLB | |
| SCHEMBL10378031 | 0.74 | ITGB3 (0.34) | CHRM5CHRM3GNAI3GNAO1GNAI1 | |
| SCHEMBL15794935 | 0.73 | CHRM5 (0.41) | CHRM5CHRM3GNAI3GNAO1GNAI1 | |
| SCHEMBL15794748 | 0.73 | CHRM5 (0.41) | CHRM5CHRM3GNAI3GNAO1GNAI1 | |
| SCHEMBL5282044 | 0.72 | CA2 (0.40) | POLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666534-A | Compositions comprising methylphenidate prodrugs, methods of making and using the same | 肯法姆股份有限公司 | 2023-01-31 | — | — | CN | disclosed |