Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | YAP1 | P46937 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24752951 | 1.00 | HCAR1 (0.41) | HCAR1USP7GPR119TGFBR1KDM4E | |
| SCHEMBL31548396 | 0.87 | USP7 (0.50) | HCAR1USP7GPR119TGFBR1KDM4E | |
| SCHEMBL24542863 | 0.86 | ACHE (0.46) | HCAR1USP7GPR119TGFBR1KDM4E | |
| SCHEMBL30120002 | 0.82 | GPR119 (0.42) | HCAR1USP7GPR119MCL1PIK3CD | |
| SCHEMBL24752971 | 0.82 | GPR119 (0.42) | HCAR1USP7GPR119MCL1PIK3CD | |
| SCHEMBL24753270 | 0.81 | HCAR1 (0.41) | HCAR1GPR119TGFBR1KDM4EPKM | |
| SCHEMBL30120095 | 0.81 | HCAR1 (0.41) | HCAR1GPR119TGFBR1KDM4EPKM | |
| SCHEMBL24752953 | 0.81 | BRAF (0.42) | GPR119CHEK2 | |
| SCHEMBL30120463 | 0.81 | BRAF (0.42) | GPR119CHEK2 | |
| SCHEMBL24542757 | 0.79 | IDO1 (0.44) | HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351583-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 Therapeutics, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261250-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |