Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24753039 | 1.00 | MAOA (0.35) | MAOAOPRL1TRPV3MAPK1NPC1 | |
| SCHEMBL22816456 | 0.84 | OPRL1 (0.45) | OPRL1TRPV3MAPK1NPC1RAB9A | |
| SCHEMBL17542866 | 0.82 | OPRL1 (0.47) | OPRL1TRPV3NPC1RAB9AMAPT | |
| SCHEMBL29932014 | 0.82 | OPRL1 (0.47) | OPRL1TRPV3NPC1RAB9AMAPT | |
| SCHEMBL24215291 | 0.81 | QPCT (0.36) | MAOAOPRL1MAPK1CRBNCHRNB2 | |
| SCHEMBL12474719 | 0.80 | TRPV3 (0.33) | TRPV3MAPK1NPC1RAB9AIKBKE | |
| SCHEMBL30084892 | 0.80 | CHRNB2 (0.41) | MAOAOPRL1MAPK1CRBNCHRNB2 | |
| SCHEMBL13014935 | 0.80 | CHRNB2 (0.41) | MAOAOPRL1MAPK1CRBNCHRNB2 | |
| SCHEMBL22089867 | 0.79 | MAOA (0.50) | MAOAOPRL1MAPK1CHRNB2CHRNA4 | |
| SCHEMBL1528692 | 0.79 | TRPV3 (0.35) | OPRL1TRPV3MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096858-A1 | COMPOUNDS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| EP-4351583-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 Therapeutics, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261250-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |