Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.42 |
| ▸ | HTR2C | P28335 | 7/20 | 0.42 |
| ▸ | HTR2B | P41595 | 7/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 10/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29164189 | 0.88 | HTR2A (0.41) | HTR2AHTR2CHTR2BFFAR2DRD2 | |
| SCHEMBL30721060 | 0.88 | HTR2A (0.41) | HTR2AHTR2CHTR2BFFAR2DRD2 | |
| SCHEMBL29164185 | 0.88 | HTR2A (0.41) | HTR2AHTR2CHTR2BFFAR2DRD2 | |
| SCHEMBL30120779 | 0.86 | HTR2A (0.45) | HTR2AHTR2CHTR2BFFAR2DRD2 | |
| SCHEMBL30120952 | 0.83 | HTR2A (0.45) | HTR2AHTR2CHTR2BFFAR2DRD2 | |
| SCHEMBL30120802 | 0.80 | FFAR2 (0.47) | HTR2AHTR2CHTR2BFFAR2 | |
| SCHEMBL23217362 | 0.78 | HTR2A (0.42) | HTR2AHTR2CHTR2BFFAR2DRD2 | |
| SCHEMBL30120770 | 0.78 | HTR2A (0.38) | HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL29164181 | 0.74 | HTR2A (0.44) | HTR2AHTR2CHTR2BFFAR2DRD2 | |
| SCHEMBL29164179 | 0.74 | HTR2A (0.44) | HTR2AHTR2CHTR2BFFAR2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313313-A1 | ARYL HETEROCYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D.E. Shaw Research, LLC (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022212296-A1 | ARYL HETEROCYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D.E. SHAW RESEARCH, LLC (US) | 2022-10-06 | — | — | WO | disclosed |