SCHEMBL30123059

CC(C)C[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)O)[C@@H](C)O)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	CALCRL	Q16602	4/20	0.61

▸	BACE1	P56817	2/20	0.54

▸	BACE2	Q9Y5Z0	1/20	0.54

▸	SLC6A2	P23975	1/20	0.54

▸	RAMP1	O60894	1/20	0.53

▸	NPY2R	P49146	7/20	0.53

▸	NPY4R	P50391	7/20	0.53

▸	NPY5R	Q15761	7/20	0.53

▸	NPY1R	P25929	5/20	0.53

▸	CALCR	P30988	3/20	0.53

▸	AGTR1	P30556	1/20	0.53

▸	AGTR2	P50052	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30607406	0.88	NPY2R (0.61)	CALCRLNPY2RNPY4RNPY5RNPY1R
SCHEMBL31020744	0.88	SLC6A2 (0.63)	CALCRLSLC6A2AGTR1AGTR2
SCHEMBL30640886	0.87	RAMP3 (0.63)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31256981	0.87	REN (0.53)	CALCRLSLC6A2
SCHEMBL30880874	0.87	CALCRL (0.61)	CALCRLBACE1BACE2SLC6A2RAMP1
SCHEMBL29679731	0.87	CALCRL (0.63)	CALCRLBACE1BACE2RAMP1
SCHEMBL29463723	0.86	AGTR2 (0.59)	CALCRLAGTR1AGTR2
SCHEMBL30883235	0.86	NPY2R (0.59)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL29410248	0.86	NPY2R (0.62)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL38650937	0.86	NTSR1 (0.58)	SLC6A2NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4370150-A1	OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS	Intervet International B.V. (NL)	2024-05-22	—	—	EP	disclosed
WO-2023285489-A1	OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS	INTERVET INTERNATIONAL B.V. (NL)	2023-01-19	—	—	WO	disclosed