Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876567 | 0.81 | SCN8A (0.39) | SCN8ATHRATHRBMAPTALDH1A1 | |
| SCHEMBL9523339 | 0.81 | SCN8A (0.39) | SCN8ATHRATHRBMAPTALDH1A1 | |
| SCHEMBL8554425 | 0.79 | SCN8A (0.43) | SCN8ATHRATHRBMAPTALDH1A1 | |
| SCHEMBL6132790 | 0.79 | MEN1 (0.54) | THRATHRBMAPTALDH1A1KDM4E | |
| SCHEMBL11241141 | 0.78 | KMT2A (0.47) | THRATHRBMAPTALDH1A1KDM4E | |
| SCHEMBL8552558 | 0.77 | SCN8A (0.40) | SCN8AMAPTALDH1A1KMT2ACYP1A2 | |
| SCHEMBL28412531 | 0.77 | HTR1A (0.41) | SCN8AMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL24942168 | 0.77 | KDM4E (0.49) | SCN8ATHRATHRBALDH1A1KDM4E | |
| SCHEMBL8137092 | 0.77 | SCN8A (0.41) | SCN8AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL28407881 | 0.75 | MAPT (0.43) | SCN8ATHRATHRBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732570-B | Imidazolidinone with antiviral activity, and synthetic method and application thereof | 湖北工程学院 | 2022-11-29 | — | — | CN | disclosed |