Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30126118 | 0.89 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3CBPIK3CGIRAK4 | |
| SCHEMBL30125919 | 0.83 | GPR119 (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGIRAK4 | |
| SCHEMBL30127290 | 0.78 | EGFR (0.49) | BTK | |
| SCHEMBL30127016 | 0.73 | USP30 (0.45) | PIK3CDPIK3CAPIK3CBPIK3CGIRAK4 | |
| SCHEMBL30126000 | 0.71 | PDE4B (0.53) | PIK3CDPIK3CAPIK3CBPIK3CGIRAK4 | |
| SCHEMBL30126197 | 0.71 | NR1H2 (0.41) | GPR119LCKJAK3BTKNR1H2 | |
| SCHEMBL30127359 | 0.71 | PDE4B (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGIRAK4 | |
| SCHEMBL22957579 | 0.70 | TP53 (0.40) | GPR119LCKJAK3BTK | |
| SCHEMBL30126933 | 0.70 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGIRAK4 | |
| SCHEMBL30880000 | 0.70 | RIPK1 (0.46) | GPR119LCKJAK3BTKNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266458-A1 | 6-HETEROCYCLOALKYL-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |