Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30125919 | 0.90 | GPR119 (0.43) | USP30PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30126118 | 0.84 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL30125930 | 0.82 | EGFR (0.49) | USP30 | |
| SCHEMBL649953 | 0.79 | GPR119 (0.47) | USP30GPR119LIPE | |
| SCHEMBL653024 | 0.79 | GPR119 (0.47) | USP30GPR119LIPE | |
| SCHEMBL650888 | 0.79 | GPR119 (0.47) | USP30GPR119LIPE | |
| SCHEMBL30126593 | 0.77 | PIK3CD (0.44) | USP30PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29781273 | 0.77 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL30127280 | 0.76 | PDE4B (0.52) | USP30PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2884981 | 0.76 | GPR119 (0.52) | USP30GPR119LIPEJAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266458-A1 | 6-HETEROCYCLOALKYL-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |