Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.55 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30216595 | 0.81 | SMN1; SMN2 (0.64) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL15875707 | 0.77 | MAOB (1.00) | MAOBMAOAALDH1A1NPC1RAB9A | |
| SCHEMBL15875495 | 0.77 | MAOB (1.00) | MAOBMAOALMNAALDH1A1NPC1 | |
| SCHEMBL13210571 | 0.76 | L3MBTL1 (0.67) | MAOBMAOALMNAALDH1A1NPC1 | |
| SCHEMBL17803491 | 0.75 | NPC1 (0.68) | MAOBMAOALMNANPC1RAB9A | |
| SCHEMBL2679067 | 0.75 | NPC1 (0.73) | MAOBMAOALMNAALDH1A1NPC1 | |
| SCHEMBL374330 | 0.75 | DHX9 (0.65) | MAOALMNAALDH1A1NPC1RAB9A | |
| SCHEMBL24934054 | 0.75 | DHX9 (0.69) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL14917101 | 0.75 | DHX9 (0.69) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL23931167 | 0.74 | KMT2A (0.55) | MAOBMAOALMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150324-A1 | 5-Membered Heteroaryl Carboxamide Compounds for Treatment of HBV | ASSEMBLY BIOSCIENCES, INC. | 2024-05-09 | — | — | US | disclosed |
| CN-115916341-A | Pyrazole carboxamide compounds for the treatment of HBV | 组装生物科学股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-11560370-B1 | 5-membered heteroaryl carboxamide compounds for treatment of HBV | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560370-B1 | 5-membered heteroaryl carboxamide compounds for treatment of HBV | HCCS, HAVCR2, MAVS | MAOB 4219/4885MAOA 4429/4885LMNA 1876/4885 |
| US-20240150324-A1 | 5-Membered Heteroaryl Carboxamide Compounds for Treatment of HBV | HCCS, HAVCR2, MAVS | MAOB 4219/4885MAOA 4429/4885LMNA 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.