Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.54 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374330 | 0.84 | DHX9 (0.65) | ALDH1A1LMNAPTPN1MAPTROCK1 | |
| SCHEMBL30129596 | 0.81 | MAOB (0.63) | SMN1; SMN2ALDH1A1LMNAMAPTDHX9 | |
| SCHEMBL359646 | 0.80 | CA1 (0.61) | ALDH1A1LMNAMAPTROCK1DHX9 | |
| SCHEMBL6819178 | 0.79 | NAMPT (0.57) | ALDH1A1LMNAMAPTROCK1DHX9 | |
| SCHEMBL31582743 | 0.78 | LMNA (0.56) | SMN1; SMN2ALDH1A1LMNAMAPTROCK1 | |
| SCHEMBL15455083 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1LMNAMAPTROCK1 | |
| SCHEMBL31457040 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1LMNAMAPTROCK1 | |
| SCHEMBL31457019 | 0.76 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1LMNAMAPTDHX9 | |
| SCHEMBL27374493 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1LMNAMAPTROCK1 | |
| SCHEMBL27374483 | 0.76 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1LMNAMAPTDHX9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313213-B | 3-amino pyrazole compound and application thereof | 上海海和药物研究开发股份有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-112313213-B | 3-amino pyrazole compound and application thereof | 上海海和药物研究开发股份有限公司 | 2023-01-31 | — | — | CN | disclosed |