Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24882742 | 0.73 | LTA4H (0.35) | NQO1NPC1MEN1KMT2AMAPT | |
| SCHEMBL24882740 | 0.73 | MAPT (0.34) | NQO1NPC1MEN1KMT2AMAPT | |
| SCHEMBL25421011 | 0.71 | DRD2 (0.45) | NQO1NPC1MEN1KMT2APKM | |
| SCHEMBL24882885 | 0.69 | CSF1R (0.41) | NPC1RAB9A | |
| SCHEMBL30131026 | 0.66 | ALDH1A1 (0.36) | NQO1MEN1KMT2APKMMAPT | |
| 1,4-Diethoxybenzene SCHEMBL11794798 | 0.65 | NQO1 (0.93) | NQO1NPC1MAPTTSHRTDP1 | |
| SCHEMBL24687082 | 0.64 | NQO1 (0.54) | NQO1TSHRTDP1LTA4H | |
| SCHEMBL21835235 | 0.62 | HRH2 (0.45) | MEN1KMT2ACASP3SENP8SENP7 | |
| 1,4-Diethoxybenzene SCHEMBL124015 | 0.62 | NQO1 (1.00) | NQO1NPC1MAPTTSHRTDP1 | |
| 1,4-Diethoxybenzene SCHEMBL28186701 | 0.62 | NQO1 (1.00) | NQO1NPC1MAPTTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250084100-A1 | METHOD FOR PREPARING NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, AND INTERMEDIATE AND USE OF COMPOUND | APPLIED PHARMACEUTICAL SCIENCE, INC. (CN) | 2025-03-13 | — | — | US | disclosed |
| EP-4368621-A1 | METHOD FOR PREPARING NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, AND INTERMEDIATE AND USE OF COMPOUND | Applied Pharmaceutical Science, Inc. (CN) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023280073-A1 | METHOD FOR PREPARING NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, AND INTERMEDIATE AND USE OF COMPOUND | 北京志健金瑞生物医药科技有限公司 | 2023-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084100-A1 | METHOD FOR PREPARING NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, AND INTERMEDIATE AND USE OF COMPOUND | RANBP1, RANBP2, RAN | NQO1 576/4885NPC1 372/4885MEN1 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.