Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166438 | 1.00 | MYC (0.41) | MYCHSD11B1KMT2AMEN1ESR1 | |
| SCHEMBL9462168 | 0.98 | HSD11B1 (0.44) | MYCHSD11B1KMT2AMEN1ESR1 | |
| SCHEMBL8417858 | 0.87 | MAPT (0.37) | MYCHSD11B1KMT2AMEN1ESR1 | |
| SCHEMBL1748 | 0.81 | MYC (0.53) | MYCHSD11B1KMT2AMEN1ESR1 | |
| SCHEMBL29392580 | 0.81 | MYC (0.53) | MYCHSD11B1KMT2AMEN1ESR1 | |
| SCHEMBL15670401 | 0.81 | ALDH1A1 (0.50) | MYCKMT2AMEN1ESR1ESR2 | |
| Ammonia Solution, Strong SCHEMBL6360239 | 0.79 | MYC (0.52) | MYCHSD11B1KMT2AMEN1ESR1 | |
| SCHEMBL6916771 | 0.79 | MYC (0.52) | MYCHSD11B1KMT2AMEN1ESR1 | |
| SCHEMBL8715920 | 0.79 | MYC (0.52) | MYCHSD11B1KMT2AMEN1ESR1 | |
| Water SCHEMBL3917281 | 0.79 | MYC (0.52) | MYCHSD11B1KMT2AMEN1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240229026-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES LTD. (SG) | 2024-07-11 | — | — | US | disclosed |
| US-11643657-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-09 | — | — | US | disclosed |
| EP-2872147-B1 | METHOD FOR MAKING CHIRAL OLIGONUCLEOTIDES | WAVE LIFE SCIENCES LTD (SG) | 2022-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240229026-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | MYC 2279/4885HSD11B1 3302/4885KMT2A 2211/4885 |
| US-11643657-B2 | Chiral control | RNGTT, POLI, NSUN3 | MYC 2279/4885HSD11B1 3302/4885KMT2A 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.