Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825998 | 0.94 | KEAP1 (0.61) | NOTUMKEAP1ABHD6MEN1MAPT | |
| SCHEMBL22784355 | 0.91 | NOTUM (0.55) | NOTUMKEAP1ABHD6MEN1MAPT | |
| SCHEMBL22784496 | 0.90 | NOTUM (0.50) | NOTUMKEAP1ABHD6MEN1MAPT | |
| SCHEMBL22785136 | 0.87 | NOTUM (0.53) | NOTUMKEAP1ABHD6MEN1MAPT | |
| SCHEMBL14393093 | 0.85 | ABHD6 (0.48) | NOTUMKEAP1ABHD6MEN1MAPT | |
| SCHEMBL417106 | 0.85 | ABHD6 (0.48) | NOTUMKEAP1ABHD6MEN1MAPT | |
| SCHEMBL13951292 | 0.85 | CHRM4 (0.52) | NOTUMKEAP1ABHD6MEN1MAPT | |
| SCHEMBL416047 | 0.85 | ABHD6 (0.48) | NOTUMKEAP1ABHD6MEN1MAPT | |
| SCHEMBL14143372 | 0.85 | ABHD6 (0.48) | NOTUMKEAP1ABHD6MEN1MAPT | |
| SCHEMBL418511 | 0.84 | KEAP1 (0.47) | NOTUMKEAP1ABHD6MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594631-A | Rosemastat key intermediate and preparation method of Rosemastat intermediate | 安徽省庆云医药股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |