Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20554382 | 1.00 | MAPT (0.42) | MAPTTDP1NPC1RAB9APKM | |
| SCHEMBL11539485 | 0.87 | MAPT (0.45) | MAPTTDP1NPC1RAB9APKM | |
| SCHEMBL20014212 | 0.79 | PIK3CA (0.56) | MAPTRAB9APKMPIK3CAMEN1 | |
| SCHEMBL25236549 | 0.79 | MAPT (0.51) | MAPTTDP1NPC1RAB9APKM | |
| SCHEMBL20554833 | 0.78 | SHBG (0.55) | MAPTNPC1RAB9APIK3CAMEN1 | |
| SCHEMBL30132562 | 0.78 | SHBG (0.55) | MAPTNPC1RAB9APIK3CAMEN1 | |
| SCHEMBL1758178 | 0.77 | MAPT (0.52) | MAPTTDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL20554639 | 0.76 | PIK3CA (0.45) | MAPTPIK3CAMEN1KMT2AALDH1A1 | |
| SCHEMBL12683255 | 0.75 | TDP1 (0.70) | MAPTTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL23120369 | 0.75 | ALDH1A1 (0.52) | MAPTTDP1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |