Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1499654 | 0.81 | HTT (0.63) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL445048 | 0.80 | NPC1 (0.72) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5233340 | 0.78 | KCNK3 (0.55) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL16761992 | 0.78 | TRPV1 (0.67) | MAPTRAB9ANPC1TRPV1 | |
| SCHEMBL31267944 | 0.78 | MAPT (0.42) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL17142822 | 0.77 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL31078069 | 0.75 | RORC (0.64) | MAPTSMN1; SMN2LMNAMAPK1KDM4E | |
| SCHEMBL1507135 | 0.74 | ALDH1A1 (0.45) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL17148240 | 0.74 | MAPT (0.68) | MAPTALDH1A1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL13699335 | 0.73 | MAPT (0.63) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |