Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395802 | 1.00 | POLB (0.58) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| Chloromethane SCHEMBL10795405 | 0.98 | POLB (0.56) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4554988 | 0.85 | KMT2A (0.69) | POLBMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL5540157 | 0.85 | ALDH1A1 (0.52) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3415036 | 0.85 | RAB9A (0.58) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5536288 | 0.84 | ALDH1A1 (0.46) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL985910 | 0.84 | TAS2R14 (0.57) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12144664 | 0.84 | EPHX2 (0.57) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3938038 | 0.82 | POLB (0.58) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL631133 | 0.82 | ALDH1A1 (0.57) | POLBMAPK1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036476-A | Preparation method of 4- (4-chlorophenoxy) -2-trifluoromethyl acetophenone | 江西天宇化工有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-111662275-B | Benzenesulfonamide IDH mutant inhibitor, preparation method and application thereof | 中国药科大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-113445066-B | Method for electrochemically synthesizing ortho-trifluoromethyl substituted aniline by using continuous flow | 南京先进生物材料与过程装备研究院有限公司 | 2022-12-20 | — | — | CN | disclosed |