Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30136232 | 1.00 | POLB (0.58) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| Chloromethane SCHEMBL10795405 | 0.98 | POLB (0.56) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4554988 | 0.85 | KMT2A (0.69) | POLBMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL5540157 | 0.85 | ALDH1A1 (0.52) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3415036 | 0.85 | RAB9A (0.58) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5536288 | 0.84 | ALDH1A1 (0.46) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL985910 | 0.84 | TAS2R14 (0.57) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12144664 | 0.84 | EPHX2 (0.57) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3938038 | 0.82 | POLB (0.58) | POLBMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL631133 | 0.82 | ALDH1A1 (0.57) | POLBMAPK1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961268-B1 | SAMPLE FIXATION AND STABILISATION | GOLDSBOROUGH ANDREW SIMON (FR) | 2018-11-21 | — | — | EP | claimed |
| EP-2961268-A1 | SAMPLE FIXATION AND STABILISATION | Goldsborough, Andrew Simon (FR) | 2016-01-06 | — | — | EP | claimed |
| US-20140295404-A1 | SAMPLE FIXATION AND STABILISATION | RNASSIST LTD. (GB) | 2014-10-02 | — | — | US | claimed |
| WO-2014131906-A1 | SAMPLE FIXATION AND STABILISATION | GOLDSBOROUGH ANDREW SIMON (FR) | 2014-09-04 | — | — | WO | claimed |
| JP-4665239-B2 | — | — | 2011-04-06 | — | — | JP | claimed |
| EP-0912492-B1 | METHOD FOR PREPARING HALOGENATED 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE DERIVATIVES | RHODIA CHIMIE SA (FR) | 2002-09-25 | — | — | EP | claimed |
| JP-2002512230-A | — | — | 2002-04-23 | — | — | JP | claimed |
| US-6191309-B1 | USING A COMPOUND OF FORMULA X2 IN A SOLVENT SELECTED FROM AN ANHYDROUS HALOGENATED HYDROCARBON, A MIXTURE OF WATER AND A HALOGENATED HYDROCARBON AND OPTIONALLY THE COMPOUND ITSELF, TO GIVE HALOGENATED 2-AMINO OR 2-ACETAMIDOTRIFLUOROMETHYLBENZENE | RHODIA CHIMIE (FR) | 2001-02-20 | — | — | US | claimed |
| EP-1071668-A1 | 5-AMINOINDENO(1,2-C)PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS | Du Pont Pharmaceuticals Company (US) | 2001-01-31 | — | — | EP | claimed |
| WO-1999054308-A1 | 5-AMINOINDENO(1,2-C)PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-10-28 | — | — | WO | claimed |
| EP-0912492-A1 | METHOD FOR PREPARING HALOGENATED 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE DERIVATIVES | RHODIA CHIMIE (FR) | 1999-05-06 | — | — | EP | claimed |
| WO-1998002409-A1 | METHOD FOR PREPARING HALOGENATED 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE DERIVATIVES | RHODIA CHIMIE (FR) | 1998-01-22 | — | — | WO | claimed |
| US-4008278-A | FROM AN AMINO-BENZOTRIFLUORIDE AND A HALOGEN SOURCE | OLIN CORPORATION (US) | 1977-02-15 | — | — | US | claimed |
| WO-2025262036-A1 | METHOD OF MANUFACTURING A PHARMACEUTICAL COMPOSITION | RNASSIST LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| EP-3827241-B1 | DISSOCIATION OF BIOLOGICAL SAMPLES | GOLDSBOROUGH ANDREW SIMON (FR) | 2024-03-13 | — | — | EP | disclosed |
| US-20240027309-A1 | SIMPLE FIXATION AND STABILISATION | RNASSIST LTD (GB) | 2024-01-25 | — | — | US | disclosed |
| EP-0143768-A1 | Preparation of ortho-(alkylthiomethyl) anilines by catalytic sulfilimine rearrangement | Monsanto Company (US) | 1985-06-05 | — | — | EP | disclosed |
| US-4480130-A | Preparation of ortho-(alkylthiomethyl) anilines by catalytic sulfilimine rearrangement | MONSANTO COMPANY (US) | 1984-10-30 | — | — | US | disclosed |
| EP-0039810-A1 | Process for the preparation of 2-trifluoromethyl aniline | BAYER AG (DE) | 1981-11-18 | — | — | EP | disclosed |
| US-4008278-A | FROM AN AMINO-BENZOTRIFLUORIDE AND A HALOGEN SOURCE | OLIN CORPORATION (US) | 1977-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240027309-A1 | SIMPLE FIXATION AND STABILISATION | EWSR1, FOSB, PAXBP1 | POLB 214/4885MAPK1 4410/4885MEN1 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.