Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6093737 | 0.86 | CA1 (0.67) | RAB9AEPHX2MAPTNPC1SMN1; SMN2 | |
| SCHEMBL558100 | 0.84 | LDHA (0.71) | RAB9AEPHX2MAPTNPC1SMN1; SMN2 | |
| SCHEMBL13054074 | 0.83 | RAB9A (0.64) | RAB9AEPHX2MAPTNPC1SMN1; SMN2 | |
| SCHEMBL6094527 | 0.83 | EPHX2 (0.58) | RAB9AEPHX2MAPTNPC1SMN1; SMN2 | |
| SCHEMBL24104135 | 0.82 | EPHX2 (0.68) | RAB9AEPHX2MAPTNPC1SMN1; SMN2 | |
| SCHEMBL30136375 | 0.82 | EPHX2 (0.68) | RAB9AEPHX2MAPTNPC1SMN1; SMN2 | |
| SCHEMBL10600068 | 0.79 | RAB9A (0.81) | RAB9AMAPTNPC1SMN1; SMN2TP53 | |
| SCHEMBL6093198 | 0.79 | EPHX2 (0.51) | RAB9AEPHX2MAPTNPC1SMN1; SMN2 | |
| SCHEMBL6067867 | 0.78 | EPHX2 (0.59) | RAB9AEPHX2MAPTNPC1SMN1; SMN2 | |
| SCHEMBL27762274 | 0.78 | RAB9A (0.60) | RAB9AMAPTNPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104496936-B | A kind of preparation method of body of Pramipexole dihydrochloride | 海南康虹医药科技开发有限公司 | 2017-11-28 | — | — | CN | disclosed |
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |