Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24756649 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL6609814 | 0.88 | NAMPT (0.52) | ALDH1A1TP53NAMPTHDAC1SMN1; SMN2 | |
| Acetic Acid SCHEMBL28111547 | 0.87 | NAMPT (0.49) | MAPTKMT2ANAMPTHDAC1SMN1; SMN2 | |
| SCHEMBL6815441 | 0.85 | ALDH1A1 (0.69) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL24364346 | 0.82 | PTPN11 (0.51) | ALDH1A1MAPTKMT2AKDM4ETP53 | |
| SCHEMBL30781986 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29141782 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7324243 | 0.80 | NAMPT (0.46) | ALDH1A1TP53NAMPTHDAC1SMN1; SMN2 | |
| SCHEMBL23213608 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL30582962 | 0.79 | FAAH (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334298-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | Scorpion Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022265993-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |