Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28111547 | 0.95 | NAMPT (0.49) | NAMPTMAPKAPK2CYP17A1HDAC1SMN1; SMN2 | |
| SCHEMBL7324243 | 0.91 | NAMPT (0.46) | NAMPTMAPKAPK2CYP17A1HDAC1SMN1; SMN2 | |
| SCHEMBL24364346 | 0.90 | PTPN11 (0.51) | NAMPTMAPKAPK2CYP17A1HDAC1SMN1; SMN2 | |
| SCHEMBL7081208 | 0.89 | NAMPT (0.46) | NAMPTMAPKAPK2CYP17A1HDAC1SMN1; SMN2 | |
| SCHEMBL30136675 | 0.88 | ALDH1A1 (0.51) | NAMPTHDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL24756649 | 0.88 | ALDH1A1 (0.51) | NAMPTHDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3328875 | 0.86 | NAMPT (0.48) | NAMPTMAPKAPK2CYP17A1HDAC1SMN1; SMN2 | |
| SCHEMBL851343 | 0.84 | DEGS1 (0.56) | NAMPTGSK3BDYRK1A | |
| SCHEMBL1126145 | 0.84 | RAB9A (0.62) | SMN1; SMN2GSK3BDYRK1ANPC1RAB9A | |
| SCHEMBL31378805 | 0.84 | KCNQ3 (0.53) | NAMPTMAPKAPK2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268469-B1 | N-(HETEROCYCLYL)BENZENE OR PYRIDINE SULPHONAMIDES AS ANTITHROMBOTIC AGENTS AND ANTICOAGULANTS | SANOFI SYNTHELABO (FR) | 2004-06-16 | — | — | EP | disclosed |