Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | CDC14B | O60729 | 1/20 | 0.34 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24756679 | 0.84 | RAB9A (0.54) | MCL1L3MBTL1HPGDKDM4ERAB9A | |
| SCHEMBL30136747 | 0.78 | ALDH1A1 (0.40) | MCL1L3MBTL1HPGDKDM4ERAB9A | |
| SCHEMBL1848231 | 0.77 | ALDH1A1 (0.46) | MCL1KDM4ERAB9AALDH1A1 | |
| SCHEMBL8082611 | 0.75 | KDM4E (0.51) | MCL1L3MBTL1HPGDKDM4ERAB9A | |
| SCHEMBL8083165 | 0.71 | LOXL2 (0.34) | MCL1LOXL2CDC14BCDC14A | |
| SCHEMBL8082589 | 0.71 | LOXL2 (0.32) | MCL1LOXL2CDC14BCDC14A | |
| SCHEMBL2089679 | 0.70 | LOXL2 (0.40) | MCL1L3MBTL1HPGDKDM4EALDH1A1 | |
| SCHEMBL8038421 | 0.70 | LOXL2 (0.40) | MCL1L3MBTL1HPGDKDM4EALDH1A1 | |
| SCHEMBL24756639 | 0.69 | RAB9A (0.34) | MCL1L3MBTL1HPGDKDM4ERAB9A | |
| SCHEMBL8081887 | 0.67 | LOXL2 (0.39) | MCL1L3MBTL1HPGDKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063810-A | ENANTIOMORPHS | SYNTHELABO (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0888324-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032870-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-09-12 | — | — | WO | disclosed |