Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28917618 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPTCYP2C9CYP1A2 | |
| SCHEMBL11292514 | 0.83 | GAA (0.51) | ALDH1A1KMT2AMAPTCYP2C9CYP1A2 | |
| SCHEMBL6524461 | 0.78 | KMT2A (0.74) | ALDH1A1KMT2AMAPTCYP2C9CYP1A2 | |
| SCHEMBL29367470 | 0.78 | KMT2A (0.74) | ALDH1A1KMT2AMAPTCYP2C9CYP1A2 | |
| SCHEMBL8897656 | 0.76 | CTRB1 (0.51) | ALDH1A1KMT2AMAPTCYP2C9CYP1A2 | |
| SCHEMBL20083679 | 0.76 | ALDH1A1 (0.63) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL20456902 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTCYP2C9CYP1A2 | |
| SCHEMBL30549154 | 0.74 | LMNA (0.63) | MAPTL3MBTL1GAALMNASMN1; SMN2 | |
| SCHEMBL3234987 | 0.74 | LMNA (0.63) | MAPTL3MBTL1GAALMNASMN1; SMN2 | |
| SCHEMBL4219713 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KMT2AMAPTCYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490640-B | Substituted benzimidazoles, compositions containing them and their use | 深圳市塔吉瑞生物医药有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-115490640-A | Substituted benzimidazoles, compositions containing them and their use | 深圳市塔吉瑞生物医药有限公司 | 2022-12-20 | — | — | CN | disclosed |