Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.42 |
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | FAP | Q12884 | 3/20 | 0.40 |
| ▸ | REN | P00797 | 3/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38658690 | 0.97 | ACE (0.44) | ACEDPP4FAPRENDPP8 | |
| SCHEMBL30051887 | 0.89 | DPP4 (0.46) | ACEDPP4FAPRENDPP8 | |
| SCHEMBL29591172 | 0.87 | PREP (0.44) | ACEDPP4FAPRENPREP | |
| SCHEMBL30138994 | 0.87 | XIAP (0.43) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL30139052 | 0.85 | NTSR1 (0.40) | ACERENPREPXIAP | |
| SCHEMBL29350794 | 0.82 | ACE (0.50) | ACEDPP4FAPRENDPP8 | |
| SCHEMBL30138987 | 0.82 | REN (0.48) | ACEDPP4FAPRENPREP | |
| SCHEMBL29464995 | 0.81 | XIAP (0.48) | ACEDPP4FAPDPP8DPP9 | |
| SCHEMBL30558183 | 0.81 | MEN1 (0.44) | ACEMAPT | |
| SCHEMBL30485831 | 0.81 | ACE (0.43) | ACEDPP4FAPRENDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181173-A | Preparation method of Tirzepatide | 深圳市健元医药科技有限公司 | 2022-10-14 | — | — | CN | claimed |